Pterostilbene
Pterostilbene is a stilbene closely related to resveratrol, with two of resveratrol's hydroxyl groups replaced by methoxy groups. It occurs in blueberries, grapes and the heartwood of Indian kino (Pterocarpus marsupium). Most commercial pterostilbene is nature-identical trans-pterostilbene made by chemical synthesis and purified to a white to off-white powder, with botanical extracts available in smaller volumes.
Suppliers sell different products under the same name. Specify the one you need.
High-purity (often 98% or more) nature-identical material, the most common grade for capsules.
Heartwood extract standardized to pterostilbene, for buyers who want a botanical source.
Pterostilbene combined with carriers or co-formers to change solubility or flow, at a lower pterostilbene percentage.
Compare each result with your own specification when the lot arrives.
Keep pterostilbene sealed in opaque containers in a cool, dry place, since light converts the trans form to cis. Shelf life and retest dates come from the supplier's specification, with trans-pterostilbene assay checked at retest.
Record trans- and cis-pterostilbene for each lot, and note whether material is synthetic or plant-derived if the label says so. Retest lots that have been stored in light or warm conditions.
Facts from regulators and standards bodies, each linked to its source.
A Health Canada natural health product monograph lists pterostilbene from the stem heartwood of Pterocarpus marsupium and synthetic pterostilbene as medicinal ingredients.
Source: webprod.hc-sc.gc.ca (opens in a new tab)This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Manufacturers and distributors whose own websites say they sell it.
Manufacturer · Rancho Santa Margarita, CA
California ingredient company that makes nature-identical specialty nutrients by fermentation and bioconversion, including ergothioneine, L-theanine, hydroxytyrosol, pterostilbene and vitamin K2.
Suppliers are in alphabetical order and none pays to appear. Each claim is checked against the supplier’s own website on the date shown. Ask for the specification sheet and a recent COA before you order, and confirm details with the supplier.
Common forms include synthetic trans-pterostilbene, pterocarpus marsupium extract and dispersible and co-crystal forms. Ask each supplier for the specification sheet of the exact grade they quote.
Expect assay (HPLC), cis-Isomer and related substances, identity, residual solvents, heavy metals and microbiology and loss on drying, each with its method, specification and result for that lot.
Keep pterostilbene sealed in opaque containers in a cool, dry place, since light converts the trans form to cis. Shelf life and retest dates come from the supplier's specification, with trans-pterostilbene assay checked at retest.
A Health Canada natural health product monograph lists pterostilbene from the stem heartwood of Pterocarpus marsupium and synthetic pterostilbene as medicinal ingredients.
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