Lactium (casein hydrolysate)
Lactium (casein hydrolysate) suppliers and sourcing guide
Lactium is a trade name for a tryptic hydrolysate of bovine alphaS1-casein, a milk protein. It is made by digesting casein with trypsin under controlled conditions, then filtering and spray-drying the hydrolysate to a cream-colored powder. The hydrolysate contains alpha-casozepine, the decapeptide corresponding to residues 91 to 100 of alphaS1-casein, which suppliers use as the marker peptide. Because it is milk-derived, it carries a milk allergen declaration.
- Category
- Specialty nutrients
- Also known as
- alphaS1-Casein tryptic hydrolysate · Milk protein hydrolysate · alpha-Casozepine · Casein decapeptide
- Facts checked
- November 2026
Forms and grades of lactium (casein hydrolysate)
Suppliers sell different products under the same name. Specify the one you need.
Hydrolysate powder
Spray-dried casein hydrolysate, the form sold to supplement makers for capsules, tablets and sachets.
Food and drink grade
The same hydrolysate specified for dairy products, drinks and bars, with attention to solubility and taste.
Blends
Hydrolysate pre-mixed with carriers or other ingredients for finished formulas.
What to check on the COA
Compare each result with your own specification when the lot arrives.
- Peptide identity
- HPLC or LC-MS peptide profile showing the alpha-casozepine marker, which ties the lot to the specified hydrolysate.
- Protein
- Total nitrogen by Kjeldahl or Dumas, reported as protein.
- Moisture and ash
- Loss on drying and ash; the powder takes up moisture readily.
- Microbiology
- Total plate count, Enterobacteriaceae, yeast and mold, and absence of Salmonella and Listeria, as for other dairy powders.
- Heavy metals
- Lead and other metals by ICP-MS against the supplier's specification.
Storage, lots and expiry
Storage and shelf life
Store the powder in sealed, moisture-proof packaging in a cool, dry place; it is hygroscopic and can cake or brown if it picks up moisture. Keep it segregated and labeled as a milk allergen. Shelf life is set by the supplier's specification, with retest for older stock.
Lots and expiry dates
Record the peptide profile or marker result, protein and moisture for each lot. Keep the milk allergen status and any dairy-source documentation (such as halal or kosher dairy status) with the lot record.
Regulatory status
Facts from regulators and standards bodies, each linked to its source.
Health Canada's Natural Health Products Ingredients Database lists alphaS1-casein tryptic hydrolysate, also called milk protein hydrolysate, as an extract under Schedule 1, item 2 of the Natural Health Products Regulations.
Source: webprod.hc-sc.gc.ca (opens in a new tab)The same entry lists alpha-casozepine as a sub-ingredient and cow (Bos taurus) milk as the source material.
Source: webprod.hc-sc.gc.ca (opens in a new tab)
This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Lactium (casein hydrolysate) suppliers
Manufacturers and distributors whose own websites say they sell it.
We are checking lactium (casein hydrolysate) suppliers now
Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.
Sell lactium (casein hydrolysate)? Request a listingFrequently asked questions
What forms of lactium (casein hydrolysate) can brands buy?
Common forms include hydrolysate powder, food and drink grade and blends. Ask each supplier for the specification sheet of the exact grade they quote.
What should the COA for lactium (casein hydrolysate) include?
Expect peptide identity, protein, moisture and ash, microbiology and heavy metals, each with its method, specification and result for that lot.
How should lactium (casein hydrolysate) be stored?
Store the powder in sealed, moisture-proof packaging in a cool, dry place; it is hygroscopic and can cake or brown if it picks up moisture. Keep it segregated and labeled as a milk allergen. Shelf life is set by the supplier's specification, with retest for older stock.
What is the regulatory status of lactium (casein hydrolysate)?
Health Canada's Natural Health Products Ingredients Database lists alphaS1-casein tryptic hydrolysate, also called milk protein hydrolysate, as an extract under Schedule 1, item 2 of the Natural Health Products Regulations. The same entry lists alpha-casozepine as a sub-ingredient and cow (Bos taurus) milk as the source material.
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