Glucoraphanin
Glucoraphanin suppliers and sourcing guide
Glucoraphanin is a glucosinolate found in broccoli and other brassicas, at its highest levels in broccoli seeds and young sprouts. It is the stable precursor that the enzyme myrosinase converts to sulforaphane when plant tissue is crushed. Commercial glucoraphanin is made by extracting broccoli seed (sometimes sprouts) with water or water-ethanol, inactivating myrosinase, then concentrating and drying the extract to a powder standardized to a stated glucoraphanin content.
- Category
- Specialty nutrients
- Also known as
- 4-(Methylsulfinyl)butyl glucosinolate · Sulforaphane glucosinolate · Broccoli seed extract · Broccoli sprout extract
- Facts checked
- November 2026
Forms and grades of glucoraphanin
Suppliers sell different products under the same name. Specify the one you need.
Broccoli seed extract
Powder standardized to a stated glucoraphanin percentage, with myrosinase inactivated during processing.
Broccoli sprout powder
Dried whole sprouts with a lower, naturally variable glucoraphanin level; some grades keep active myrosinase.
Glucoraphanin with myrosinase source
Glucoraphanin extract blended with a myrosinase-active ingredient such as mustard seed or broccoli sprout powder, sold for products meant to form sulforaphane when mixed with water.
Organic grades
Extracts or sprout powders made from certified organic seed.
What to check on the COA
Compare each result with your own specification when the lot arrives.
- Glucoraphanin assay
- Glucoraphanin content by HPLC, either intact or as the desulfo form (ISO 9167 style method); ask which method was used.
- Myrosinase activity or sulforaphane yield
- For grades that state active enzyme, a conversion test that measures sulforaphane formed by HPLC after hydration.
- Moisture
- Loss on drying; moisture above spec can let residual enzyme activity break down glucoraphanin.
- Heavy metals and pesticides
- Lead, arsenic, cadmium and mercury by ICP-MS, and pesticide residues for seed-derived material.
- Microbiology
- Total plate count, yeast and mold, and absence of Salmonella, E. coli and Listeria, which matters for sprout-derived products.
Storage, lots and expiry
Storage and shelf life
Keep glucoraphanin powders sealed in a cool, dry place away from light; dry glucoraphanin is stable, but moisture lets any remaining myrosinase convert it. Products with an added myrosinase source need tighter moisture control. Shelf life follows the supplier's specification, with retest of glucoraphanin (and enzyme activity where claimed) for older stock.
Lots and expiry dates
Record the glucoraphanin result and method for each lot, since seed variety and crop year change the level. For grades with active myrosinase, also record the enzyme or conversion result, which can fall with age.
Regulatory status
Facts from regulators and standards bodies, each linked to its source.
Health Canada's Natural Health Products Ingredients Database lists glucoraphanin, proper name 4-(methylsulfinyl)butyl glucosinolate (CAS 21414-41-5), as an isolate under Schedule 1, item 2 of the Natural Health Products Regulations.
Source: webprod.hc-sc.gc.ca (opens in a new tab)The same entry lists broccoli (Brassica oleracea var. italica) flower, seed and sprout as source materials.
Source: webprod.hc-sc.gc.ca (opens in a new tab)
This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Glucoraphanin suppliers
Manufacturers and distributors whose own websites say they sell it.
We are checking glucoraphanin suppliers now
Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.
Sell glucoraphanin? Request a listingFrequently asked questions
What forms of glucoraphanin can brands buy?
Common forms include broccoli seed extract, broccoli sprout powder, glucoraphanin with myrosinase source and organic grades. Ask each supplier for the specification sheet of the exact grade they quote.
What should the COA for glucoraphanin include?
Expect glucoraphanin assay, myrosinase activity or sulforaphane yield, moisture, heavy metals and pesticides and microbiology, each with its method, specification and result for that lot.
How should glucoraphanin be stored?
Keep glucoraphanin powders sealed in a cool, dry place away from light; dry glucoraphanin is stable, but moisture lets any remaining myrosinase convert it. Products with an added myrosinase source need tighter moisture control. Shelf life follows the supplier's specification, with retest of glucoraphanin (and enzyme activity where claimed) for older stock.
What is the regulatory status of glucoraphanin?
Health Canada's Natural Health Products Ingredients Database lists glucoraphanin, proper name 4-(methylsulfinyl)butyl glucosinolate (CAS 21414-41-5), as an isolate under Schedule 1, item 2 of the Natural Health Products Regulations. The same entry lists broccoli (Brassica oleracea var. italica) flower, seed and sprout as source materials.
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