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Dihydromyricetin (DHM)

Dihydromyricetin (DHM) suppliers and sourcing guide

Dihydromyricetin (DHM), also called ampelopsin, is a flavanonol found in the fruit stalks and seeds of the Japanese raisin tree (Hovenia dulcis) and at high levels in the leaves and stems of vine tea (Nekemias grossedentata, formerly Ampelopsis grossedentata). Most commercial DHM is extracted from vine tea with water or ethanol and purified by crystallization to a high-purity powder. Hovenia extracts standardized to DHM are also sold.

See suppliersWhat to ask for on the COA
Also known as
Ampelopsin · DHM · Hovenia dulcis extract · Vine tea extract · CAS 27200-12-0
Facts checked
November 2026

Forms and grades of dihydromyricetin (dhm)

Suppliers sell different products under the same name. Specify the one you need.

  • Purified DHM

    Crystalline powder from vine tea at high purity, the main traded form.

  • Hovenia dulcis extract

    Extract of fruit stalks or seeds standardized to a DHM percentage.

  • Vine tea extract

    Lower-purity extracts with DHM and other flavonoids.

  • Water-dispersible grades

    DHM processed or formulated to disperse in drinks, since pure DHM dissolves poorly in cold water.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Assay (HPLC)
DHM content by HPLC against a reference standard.
Identity
HPLC fingerprint or IR spectrum, and botanical identity of the source plant.
Residual solvents
Extraction and crystallization solvents such as ethanol, against USP <467> or the buyer's limits.
Pesticide residues
Multi-residue screen for plant-derived material.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS, checked against the supplier specification and the buyer's own limits.
Microbiology
Total plate count, yeast and mold, coliforms or E. coli, and Salmonella, against the supplier specification.

Storage, lots and expiry

Storage and shelf life

Store sealed in a cool, dry place protected from light; DHM can darken with light and heat. Shelf life and retest date come from the supplier's specification.

Lots and expiry dates

Record DHM assay and source plant (vine tea or Hovenia) for each lot, since the label name and botanical declaration depend on the source. Rotate first-expiry-first-out.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Dihydromyricetin (DHM) suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking dihydromyricetin (dhm) suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

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Frequently asked questions

What forms of dihydromyricetin (dhm) can brands buy?

Common forms include purified DHM, hovenia dulcis extract, vine tea extract and water-dispersible grades. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for dihydromyricetin (dhm) include?

Expect assay (HPLC), identity, residual solvents, pesticide residues, heavy metals and microbiology, each with its method, specification and result for that lot.

How should dihydromyricetin (dhm) be stored?

Store sealed in a cool, dry place protected from light; DHM can darken with light and heat. Shelf life and retest date come from the supplier's specification.

What is the regulatory status of dihydromyricetin (dhm)?

Health Canada's Natural Health Products Ingredients Database lists dihydromyricetin (common names ampelopsin and dihydromyricetin) as an isolate. The same entry lists Hovenia dulcis fruit, fruit stalk and seed and Nekemias grossedentata leaf and stem as source materials.

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