Artichoke leaf
Artichoke leaf comes from Cynara cardunculus (often listed as Cynara scolymus), the globe artichoke, grown in Mediterranean Europe, North Africa and South America. The basal leaves are dried and sold as powder or extracted with water or water-alcohol, then concentrated and dried. Extracts are usually standardized to caffeoylquinic acids such as chlorogenic acid and cynarin, measured by HPLC.
Suppliers sell different products under the same name. Specify the one you need.
Dried, milled leaf, sold by mesh and not standardized.
Water or hydroalcoholic extract with a declared percentage of caffeoylquinic acids or cynarin by HPLC.
Liquid extract for tinctures and bitters, sold by drug-to-extract ratio.
Leaf or extract from certified organic farms, with the organic certificate tied to the lot.
Compare each result with your own specification when the lot arrives.
Store powder and extract sealed in lined containers away from heat, light and humidity; the extract is hygroscopic. Caffeoylquinic acids degrade with heat and moisture, so reseal opened containers promptly. Suppliers set a shelf life or retest date and repeat the marker assay at retest.
Marker content varies with cultivar, leaf age and drying, so check each lot's assay against your spec. Record supplier lot, plant part and solvent, and rotate first-expiry-first-out.
Facts from regulators and standards bodies, each linked to its source.
21 CFR 172.510 lists artichoke leaves (Cynara scolymus) among natural flavoring substances, limited to use in alcoholic beverages.
Source: ecfr.gov (opens in a new tab)FDA's Substances Added to Food inventory lists artichoke leaves (Cynara scolymus) with the technical effect flavoring agent or adjuvant, citing 21 CFR 172.510.
Source: hfpappexternal.fda.gov (opens in a new tab)Health Canada's globe artichoke natural health product monograph lists Cynara cardunculus with the dried or fresh leaf as the source part.
Source: webprod.hc-sc.gc.ca (opens in a new tab)This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Manufacturers and distributors whose own websites say they sell it.
Manufacturer · Belpasso, Italy
Sells it as altilix
Bionap is a Sicilian producer of standardized extracts from Mediterranean plants and fruits, such as artichoke leaf, bergamot juice, prickly pear cladodes, olive leaf and mullein, for supplement, personal care and animal health makers.
Suppliers are in alphabetical order and none pays to appear. Each claim is checked against the supplier’s own website on the date shown. Ask for the specification sheet and a recent COA before you order, and confirm details with the supplier.
Common forms include leaf powder, standardized dry extract, fluid extract and organic. Ask each supplier for the specification sheet of the exact grade they quote.
Expect identity (HPTLC), marker assay (HPLC), residual solvents, heavy metals and microbiology, each with its method, specification and result for that lot.
Store powder and extract sealed in lined containers away from heat, light and humidity; the extract is hygroscopic. Caffeoylquinic acids degrade with heat and moisture, so reseal opened containers promptly. Suppliers set a shelf life or retest date and repeat the marker assay at retest.
21 CFR 172.510 lists artichoke leaves (Cynara scolymus) among natural flavoring substances, limited to use in alcoholic beverages. FDA's Substances Added to Food inventory lists artichoke leaves (Cynara scolymus) with the technical effect flavoring agent or adjuvant, citing 21 CFR 172.510. Health Canada's globe artichoke natural health product monograph lists Cynara cardunculus with the dried or fresh leaf as the source part.
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