Thiamine mononitrate
Thiamine mononitrate suppliers and sourcing guide
Thiamine mononitrate is the nitrate salt of thiamine (vitamin B1), a white crystalline powder. It is made from thiamine hydrochloride by dissolving it in alkaline solution and precipitating the nitrate salt with nitric acid. It is less hygroscopic and more stable in dry form than the hydrochloride, but less soluble in water, so it is the usual thiamine source for flour enrichment, tablets, capsules and dry premixes.
- Category
- Vitamins and minerals
- Also known as
- Thiamine nitrate · Vitamin B1 mononitrate · CAS 532-43-4
- Facts checked
- November 2026
Forms and grades of thiamine mononitrate
Suppliers sell different products under the same name. Specify the one you need.
USP / FCC grade
Fine crystalline powder tested to pharmacopeia or Food Chemicals Codex monographs, for supplements and foods.
Granular or direct-compression grade
Granulated material that flows and compresses well in tablets.
Enrichment premix
Thiamine mononitrate blended with other enrichment nutrients by premix suppliers for flour and grain products.
Feed grade
Lower-cost grade for animal nutrition; not meant for human food or supplements.
What to check on the COA
Compare each result with your own specification when the lot arrives.
- Assay
- Thiamine salt content on a dried or anhydrous basis by HPLC or by the titration or UV method in the USP or FCC monograph.
- Identity
- Infrared spectrum against a reference standard, plus the monograph test for the chloride or nitrate counter-ion.
- Loss on drying
- Moisture by loss on drying, as set in the monograph.
- Chloride limit
- Residual chloride from the hydrochloride starting material, a monograph purity test.
- Residue on ignition
- Inorganic residue, a standard monograph purity test.
- Heavy metals
- Lead and other elemental impurities by ICP-MS against the monograph or supplier limit.
Storage, lots and expiry
Storage and shelf life
Thiamine mononitrate is fairly stable as a dry powder; keep containers tightly closed in a cool, dry place away from light. In finished products it breaks down faster with heat, neutral or alkaline pH and sulfites. Suppliers set shelf life or a retest date, with assay as the usual retest check.
Lots and expiry dates
Record assay and loss on drying for each lot. Keep the mononitrate and hydrochloride as separate items, since their thiamine content per gram differs and swapping them changes the amount delivered.
Regulatory status
Facts from regulators and standards bodies, each linked to its source.
21 CFR 184.1878 describes thiamine mononitrate as prepared from thiamine hydrochloride and affirms it as GRAS as a nutrient supplement, used in food with no limitation other than current good manufacturing practice.
Source: ecfr.gov (opens in a new tab)Health Canada's Multi-Vitamin/Mineral Supplements monograph lists thiamine mononitrate as a source ingredient for thiamine (vitamin B1).
Source: webprod.hc-sc.gc.ca (opens in a new tab)21 CFR 101.9(c)(8)(iv) sets the Reference Daily Intake for thiamin at 1.2 mg for adults and children 4 years and older.
Source: ecfr.gov (opens in a new tab)
This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Thiamine mononitrate suppliers
Manufacturers and distributors whose own websites say they sell it.
We are checking thiamine mononitrate suppliers now
Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.
Sell thiamine mononitrate? Request a listingFrequently asked questions
What forms of thiamine mononitrate can brands buy?
Common forms include uSP / FCC grade, granular or direct-compression grade, enrichment premix and feed grade. Ask each supplier for the specification sheet of the exact grade they quote.
What should the COA for thiamine mononitrate include?
Expect assay, identity, loss on drying, chloride limit, residue on ignition and heavy metals, each with its method, specification and result for that lot.
How should thiamine mononitrate be stored?
Thiamine mononitrate is fairly stable as a dry powder; keep containers tightly closed in a cool, dry place away from light. In finished products it breaks down faster with heat, neutral or alkaline pH and sulfites. Suppliers set shelf life or a retest date, with assay as the usual retest check.
What is the regulatory status of thiamine mononitrate?
21 CFR 184.1878 describes thiamine mononitrate as prepared from thiamine hydrochloride and affirms it as GRAS as a nutrient supplement, used in food with no limitation other than current good manufacturing practice. Health Canada's Multi-Vitamin/Mineral Supplements monograph lists thiamine mononitrate as a source ingredient for thiamine (vitamin B1). 21 CFR 101.9(c)(8)(iv) sets the Reference Daily Intake for thiamin at 1.2 mg for adults and children 4 years and older.
More vitamins and minerals
- Magnesium GlycinateMagnesium bisglycinate · Magnesium bisglycinate chelate
- Vitamin CL-ascorbic acid · Ascorbic acid
- Vitamin D3Cholecalciferol · Colecalciferol
- ZincZinc citrate · Zinc gluconate
- Vitamin A palmitateRetinyl palmitate · Retinol palmitate
- Vitamin A acetateRetinyl acetate · Retinol acetate
- Beta-caroteneβ-Carotene · all-trans-beta-carotene
- Vitamin D2Ergocalciferol · Calciferol
- Vitamin E (d-alpha tocopherol)d-alpha-tocopherol · RRR-alpha-tocopherol
- Mixed tocopherolsTocopherols concentrate, mixed · Mixed tocopherol concentrate
- Vitamin K1Phylloquinone · Phytonadione
- Vitamin K2 (MK-7)Menaquinone-7 · MK-7
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