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N-acetyl L-tyrosine

N-acetyl L-tyrosine suppliers and sourcing guide

N-acetyl L-tyrosine is L-tyrosine with an acetyl group on its amino nitrogen. It is made by acetylating L-tyrosine, usually with acetic anhydride, then purifying and crystallizing the product. It is far more water-soluble than L-tyrosine, so brands buy it as a white powder for drink mixes and liquid formats as well as capsules.

Also known as
NALT · N-Acetyl-L-tyrosine · Acetyl tyrosine
Facts checked
November 2026

Forms and grades of n-acetyl L-tyrosine

Suppliers sell different products under the same name. Specify the one you need.

  • Crystalline powder

    Standard NALT powder for capsules, drink mixes and liquids.

  • Fine powder

    Milled grades for capsule filling and fast dissolution.

  • Grades by tyrosine source

    NALT made from fermentation-derived L-tyrosine, for buyers who need a vegan source statement.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Identity
Infrared spectrum matched to a reference standard, plus specific optical rotation, which confirms the L-form of N-acetyl-L-tyrosine.
Assay
Purity on a dried basis by HPLC, reported against the USP, FCC or supplier specification.
Related substances
Free L-tyrosine and other related substances by HPLC, which show unreacted starting material or hydrolysis.
Loss on drying and residue on ignition
Moisture by loss on drying and inorganic residue as residue on ignition (sulfated ash), with chloride and sulfate where the specification lists them.
Heavy metals and microbiology
Lead, arsenic, cadmium and mercury by ICP-MS, plus total plate count, yeast and mold, E. coli and Salmonella.
Residual solvents
Acetic acid and any process solvents by GC, against the supplier's specification.

Storage, lots and expiry

Storage and shelf life

Store N-acetyl L-tyrosine in tightly closed, lined containers in a cool, dry place away from light and strong odors, and reseal opened packs promptly. Shelf life or retest date is set by the supplier's specification; assay, loss on drying and micro are the usual retest points for older stock.

Lots and expiry dates

Record assay and free L-tyrosine for each lot, and calculate any tyrosine-equivalent label amounts from the measured assay. Rotate stock FEFO.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

N-acetyl L-tyrosine suppliers

Manufacturers and distributors whose own websites say they sell it.

Suppliers are in alphabetical order and none pays to appear. Each claim is checked against the supplier’s own website on the date shown. Ask for the specification sheet and a recent COA before you order, and confirm details with the supplier.

Frequently asked questions

What forms of n-acetyl L-tyrosine can brands buy?

Common forms include crystalline powder, fine powder and grades by tyrosine source. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for n-acetyl L-tyrosine include?

Expect identity, assay, related substances, loss on drying and residue on ignition, heavy metals and microbiology and residual solvents, each with its method, specification and result for that lot.

How should n-acetyl L-tyrosine be stored?

Store N-acetyl L-tyrosine in tightly closed, lined containers in a cool, dry place away from light and strong odors, and reseal opened packs promptly. Shelf life or retest date is set by the supplier's specification; assay, loss on drying and micro are the usual retest points for older stock.

What is the regulatory status of n-acetyl L-tyrosine?

Health Canada's L-Tyrosine natural health product monograph lists N-acetyl-L-tyrosine as a source ingredient for L-tyrosine. Health Canada's Workout Supplements monograph also lists N-acetyl-L-tyrosine as a source ingredient for L-tyrosine.

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